Hole mobilities of periodic models of DNA double helices in the nucleosomes at different temperatures
نویسندگان
چکیده
Using the Hartree-Fock crystal orbital method band structures of poly(G̃− C̃) and poly(Ã− T̃) were calculated (G̃, etc. means a nucleotide) including water molecules and Na ions. Due to the close packing of DNA in the ribosomes the motion of the double helix and the water molecules around it are strongly restricted, therefore the band picture can be used. The mobilities were calculated from the highest filled bands. The hole mobilities increase with decreasing temperatures. They are of the same order of magnitude as those of poly(Ã) and poly(T̃). For poly(G̃) the result is ∼5 times larger than in the poly(G̃− C̃) case.
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ABSTRACT In eukaryote cells, DNA is complexed with a series of basic proteins making units of chromatin structure named nucleosomes. In addition, nonhistone proteins with different function are the components of chromatin. Among these proteins, a group with a low mobility on gel electrophoresis have been identified and named LMG. In this study a LMG protein with a molecular weigh of 160 ...
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